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My DH just finished his last appointment for Hodgkins. We were surprised and had just bought our house when we found out what he had. I had a 3 yo and a 6 yo and was basically left to do everything myself around the house. As previous posters have said even if you offer they will probably not take you up. You basically have to show up and offer some help. Helping with the kids is a great idea. My DH was okay immediately after Chemo and then over the next few days it was rough. He needed lots of sleep and with kids it's tough.
I would have appreciated someone asking to take the kids for an afternoon, or showing up with a few snacks and groceries for the kids. DH needed things like water and yogurt. Someone to help around the house would have been nice too, especially when we were driving to specialists for tests. But nobody wants to ask anyone for these things because we feel bad. If you don't know the family really well, then maybe the class could ask for everyone to donate some items for a gift basket. Gift cards for gas, groceries, etc. would be nice. The chemo process is fairly long, around 4-6 hours for us, and sometimes the drive is another hour or so. With gas prices so high it might be a nice gesture to give a gas card. Both hubby and wife will be going through a rough time and when hubby is with wife he will need something to do like books, puzzle books, etc. Wife will probably get something to relax her while she receives the 4 med's and will probably be sleeping so maybe some nice cozy slippers.
I hope this helps. And you are right, Hodgkins has a very high success rate. My DH will be in complete remission this year, fingers crossed!
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