I know personally of one company who has let go all of their research & development staff, ALL of them, they will finish up their current line of medications, then they are out of the game. This company is in multiple lines of healthcare, they see the writings on the wall with pharma & are getting out while the getting is good. This is purely from a business standpoint & since I have stock in that company, I happen to agree with them. Once you limit market capabilities, you limit the risk companies are willing to invest.

I have to run or I'd answer your other questions.