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Originally Posted by marilynk  "Tweekers" typically refer to meth addicts. It's been my experience that Meth addicts keep odd hours, can't/don't sleep, are paranoid (people are "watching" them), lose weight (they don't eat), begin having serious dental issues (teeth start rotting and/or falling out), and develop signficant skin problems (usually from "picking" at their skin to get the "bugs" from underneath their skin).
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This is very interesting. I had a Aunt who picked at her skin all the time. She also lost weight and couldn't be still. We always wondered what drug she was doing.